Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 7/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909359 | 0.81 | POLB (0.60) | MTNR1BMTNR1AHPGDHSD17B10BACE1 | |
| SCHEMBL27512435 | 0.80 | MTNR1B (0.57) | MTNR1BMTNR1AHSD17B10MAPTBACE1 | |
| SCHEMBL9854748 | 0.77 | MTNR1A (0.49) | MTNR1BMTNR1AHPGDHSD17B10LMNA | |
| SCHEMBL8675359 | 0.76 | PKM (0.61) | MTNR1BMTNR1ALMNAMAPTL3MBTL1 | |
| SCHEMBL9517976 | 0.75 | ELANE (0.59) | MTNR1BMTNR1ALMNAMAPTL3MBTL1 | |
| SCHEMBL48106 | 0.75 | MTNR1A (0.59) | MTNR1BMTNR1AHSD17B10 | |
| SCHEMBL10908806 | 0.75 | ALDH1A1 (0.50) | MTNR1BMTNR1AHPGDHSD17B10LMNA | |
| SCHEMBL3961218 | 0.74 | FFAR1 (0.64) | MAPTNPC1RAB9A | |
| Nitrogen SCHEMBL11410837 | 0.74 | MAPT (0.50) | MTNR1BMTNR1AMAPTNPC1RAB9A | |
| SCHEMBL3957122 | 0.73 | HSD17B10 (0.56) | MTNR1BMTNR1AHPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428423-A2 | Aryloxy alkyl benzenes, processes for their preparation and pharmaceutical compositions containing them | LIPHA S.A. (FR) | 1991-05-22 | — | — | EP | disclosed |