Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | CHAT | P28329 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10521942 | 0.80 | HTR2A (0.43) | RIPK1HTR2ANPC1MTORTP53 | |
| SCHEMBL10521936 | 0.80 | HTR2A (0.43) | RIPK1HTR2ANPC1MTORTP53 | |
| SCHEMBL314557 | 0.76 | HTR2A (0.41) | HTR2ATRPA1ALDH1A1TSHRTP53 | |
| SCHEMBL6028210 | 0.74 | HTR2A (0.39) | HTR2AALDH1A1TSHRNPC1MTOR | |
| SCHEMBL7740381 | 0.74 | TRPA1 (0.42) | HTR2ATRPA1ALDH1A1TSHRAHR | |
| SCHEMBL555263 | 0.71 | HTR2A (0.48) | HTR2AHRH1SLC6A3ALDH1A1TSHR | |
| SCHEMBL9537967 | 0.71 | MEN1 (0.42) | HTR2ATRPA1NPC1MTORTP53 | |
| SCHEMBL11349841 | 0.69 | ALDH1A1 (0.46) | OPRK1ALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL315078 | 0.69 | HTR2A (0.41) | HTR2ACHATALDH1A1TSHRAHR | |
| SCHEMBL27460410 | 0.68 | LMNA (0.41) | HTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599335-A | FUNGICIDES, BACTERICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1986-07-08 | — | — | US | claimed |
| CN-105492971-B | The method of the orientation of block copolymer mesoscopic structure is controlled by random copolymer | 阿科玛法国公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-105579498-B | Method for controlling the period characterizing the morphology obtained from a blend of block copolymers and of (co) polymers of one of the blocks | 阿科玛法国公司 | 2019-06-04 | — | — | CN | disclosed |
| US-10301433-B2 | Curable organopolysiloxane compositions | WACKER CHEMIE AG (DE) | 2019-05-28 | — | — | US | disclosed |
| CN-105980495-B | The method for controlling substrate surface energy | 阿科玛法国公司 | 2018-12-25 | — | — | CN | disclosed |
| EP-3172178-B1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | WACKER CHEMIE AG (DE) | 2018-09-12 | — | — | EP | disclosed |
| US-20170210856-A1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | WACKER CHEMIE AG (DE) | 2017-07-27 | — | — | US | disclosed |
| EP-3038993-B1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | WACKER CHEMIE AG (DE) | 2017-05-31 | — | — | EP | disclosed |
| EP-3172178-A1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | Wacker Chemie AG (DE) | 2017-05-31 | — | — | EP | disclosed |
| US-9617186-B2 | Curable organopolysiloxane compositions | WACKER CHEMIE AG (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20160207832-A1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | WACKER CHEMIE AG (DE) | 2016-07-21 | — | — | US | disclosed |
| WO-2016012305-A1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | WACKER CHEMIE AG (DE) | 2016-01-28 | — | — | WO | disclosed |