Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913843 | 0.92 | ESR1 (0.48) | ALDH1A1POLBESR1ESR2KDM4E | |
| SCHEMBL10909875 | 0.84 | POLB (0.44) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL10909557 | 0.84 | POLB (0.56) | POLB | |
| SCHEMBL10913065 | 0.83 | MAPT (0.59) | ALDH1A1HDAC7MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8091541 | 0.80 | POLB (0.55) | POLB | |
| SCHEMBL10912020 | 0.79 | ALDH1A1 (0.48) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL9631706 | 0.79 | HDAC3 (0.59) | ALDH1A1POLBESR1ESR2KDM4E | |
| SCHEMBL10912457 | 0.77 | RAB9A (0.43) | ALDH1A1POLBMEN1KMT2AHDAC7 | |
| Dimethylamine SCHEMBL10912051 | 0.77 | RPS6KA2 (0.49) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL10909819 | 0.76 | KDM4E (0.73) | ALDH1A1POLBESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |