Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3774059 | 0.90 | ALDH1A1 (0.52) | MAPTRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL10912457 | 0.84 | RAB9A (0.43) | MAPTRAB9ASMN1; SMN2ALDH1A1HDAC7 | |
| SCHEMBL10909622 | 0.83 | CA1 (0.55) | SMN1; SMN2ALDH1A1TDP1L3MBTL1LMNA | |
| SCHEMBL10909557 | 0.83 | POLB (0.56) | — | |
| SCHEMBL10909596 | 0.83 | ALDH1A1 (0.48) | MAPTRAB9ASMN1; SMN2ALDH1A1HDAC7 | |
| SCHEMBL10909875 | 0.83 | POLB (0.44) | MAPTRAB9ASMN1; SMN2CYP2C19ALDH1A1 | |
| SCHEMBL3779981 | 0.80 | POLB (0.47) | MAPTRAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8091541 | 0.79 | POLB (0.55) | — | |
| SCHEMBL1569305 | 0.78 | ALDH1A1 (0.56) | MAPTRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL490841 | 0.78 | ALDH1A1 (0.56) | MAPTRAB9ASMN1; SMN2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |