Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911693 | 0.92 | ACHE (0.42) | POLBALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10909596 | 0.84 | ALDH1A1 (0.48) | POLBHDAC7ALDH1A1KMT2AKDM4E | |
| SCHEMBL10909557 | 0.84 | POLB (0.56) | POLBACHE | |
| SCHEMBL10913065 | 0.83 | MAPT (0.59) | HDAC7ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8091541 | 0.80 | POLB (0.55) | POLBACHE | |
| SCHEMBL10912020 | 0.79 | ALDH1A1 (0.48) | POLBALDH1A1KMT2AKDM4EMEN1 | |
| Dimethylamine SCHEMBL10912051 | 0.77 | RPS6KA2 (0.49) | POLBALDH1A1KMT2AKDM4EMEN1 | |
| Dimethylamine SCHEMBL10913831 | 0.76 | POLB (0.46) | POLBALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10913514 | 0.76 | HRH3 (0.52) | POLBACHE | |
| SCHEMBL10913826 | 0.76 | TERT (0.47) | POLBALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |