Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347176 | 0.93 | TIMP3 (0.45) | DHODHAPEX1RAB9ANPC1L3MBTL1 | |
| SCHEMBL11427857 | 0.87 | CASP6 (0.44) | DHODHAPEX1RAB9ANPC1MEN1 | |
| SCHEMBL11433915 | 0.84 | CASP6 (0.44) | DHODHAPEX1RAB9ANPC1MEN1 | |
| SCHEMBL10907696 | 0.84 | CASP6 (0.44) | DHODHAPEX1RAB9ANPC1L3MBTL1 | |
| SCHEMBL11426456 | 0.84 | MEN1 (0.55) | RAB9ANPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL10909128 | 0.84 | CASP6 (0.50) | APEX1TIMP3CASP6CTDSP1SNCA | |
| SCHEMBL10908181 | 0.83 | CASP6 (0.48) | DHODHAPEX1L3MBTL1MEN1KMT2A | |
| SCHEMBL10908640 | 0.83 | L3MBTL1 (0.44) | DHODHAPEX1RAB9ANPC1L3MBTL1 | |
| SCHEMBL10907535 | 0.83 | CASP6 (0.43) | DHODHAPEX1L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL11423192 | 0.82 | SMN1; SMN2 (0.67) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |