Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11427857 | 0.91 | CASP6 (0.44) | CASP6CTDSP1RAB9ANPC1MEN1 | |
| SCHEMBL11434182 | 0.85 | CASP6 (0.60) | CASP6CTDSP1RAB9AMEN1KMT2A | |
| SCHEMBL11347176 | 0.84 | TIMP3 (0.45) | CASP6CTDSP1RAB9ANPC1MEN1 | |
| SCHEMBL10909653 | 0.84 | DHODH (0.45) | CASP6CTDSP1RAB9ANPC1MEN1 | |
| SCHEMBL11423192 | 0.84 | SMN1; SMN2 (0.67) | CTDSP1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11440636 | 0.83 | CASP6 (0.46) | CASP6CTDSP1MEN1KMT2AAPEX1 | |
| SCHEMBL11136921 | 0.83 | APEX1 (0.65) | CASP6CTDSP1RAB9ANPC1MEN1 | |
| SCHEMBL11425755 | 0.82 | MAPT (0.42) | CASP6CTDSP1RAB9ANPC1MEN1 | |
| SCHEMBL11786406 | 0.82 | L3MBTL1 (0.49) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL11425057 | 0.82 | KAT6A (0.52) | CASP6CTDSP1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |