Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 8/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5614120 | 0.88 | NT5E (0.42) | NT5EPRMT5WDR77LMNAMTOR | |
| SCHEMBL770117 | 0.78 | LMNA (0.62) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL2577234 | 0.78 | LMNA (0.62) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL4946500 | 0.78 | NT5E (0.65) | NT5ELMNAMTORTHRBMDM2 | |
| SCHEMBL770116 | 0.78 | LMNA (0.62) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL4428196 | 0.77 | LMNA (0.43) | NT5EPRMT5WDR77LMNAMTOR | |
| SCHEMBL1740045 | 0.74 | ALB (0.45) | NT5EPRMT5WDR77LMNAMTOR | |
| SCHEMBL11208918 | 0.72 | LMNA (0.49) | LMNAMTORTHRBMDM2NCOA1 | |
| Hydrochloric Acid SCHEMBL10887377 | 0.71 | LMNA (0.48) | LMNAMTORTHRBMDM2NCOA1 | |
| Hydrochloric Acid SCHEMBL10887370 | 0.71 | LMNA (0.48) | LMNAMTORTHRBMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4617189-A | Use of selenium-containing compounds for negating the toxic effects of platinum compounds used in chemotherapy, and a novel selenium-containing platinum compound and use thereof as an anti-cancer medicine | STOCKEL RICHARD F (US) | 1986-10-14 | — | — | US | disclosed |
| US-4536571-A | SEFL-DETOXIFYING ANTICARCINOGENIC AGENT | STOCKEL RICHARD F (US) | 1985-08-20 | — | — | US | disclosed |