Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909875 | 0.92 | POLB (0.44) | ACHEALDH1A1POLBLMNARAB9A | |
| SCHEMBL10913843 | 0.83 | ESR1 (0.48) | ALDH1A1POLBLMNAAGTR1KDM4E | |
| SCHEMBL10913972 | 0.83 | ALOX5 (0.56) | ACHEPOLBALOX5RAB9AKDM4E | |
| SCHEMBL3774059 | 0.82 | ALDH1A1 (0.52) | ALDH1A1LMNAAGTR1RAB9AKMT2A | |
| SCHEMBL10912534 | 0.78 | HPGD (0.49) | ACHEALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL10953057 | 0.77 | DRD2 (0.45) | — | |
| SCHEMBL10912368 | 0.77 | ALDH1A1 (0.41) | ALDH1A1POLBRAB9AMEN1KMT2A | |
| Dimethylamine SCHEMBL10909606 | 0.76 | RPS6KA2 (0.51) | ALDH1A1POLBLMNAAGTR1RAB9A | |
| SCHEMBL10909593 | 0.75 | KMT2A (0.43) | ACHEMEN1KMT2AMAPT | |
| SCHEMBL10909557 | 0.75 | POLB (0.56) | ACHEPOLBALOX5CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |