Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912020 | 0.93 | ALDH1A1 (0.48) | HPGDHSD17B10ALDH1A1POLBACHE | |
| SCHEMBL10913473 | 0.79 | PDK2 (0.44) | HPGDHSD17B10ALDH1A1POLBMAPK1 | |
| SCHEMBL10911693 | 0.78 | ACHE (0.42) | ALDH1A1POLBACHEKDM4EKMT2A | |
| SCHEMBL10913843 | 0.78 | ESR1 (0.48) | ALDH1A1POLBKDM4EPKMKMT2A | |
| SCHEMBL8638609 | 0.77 | CYP1A2 (0.40) | HPGDHSD17B10ALDH1A1POLBACHE | |
| SCHEMBL8636623 | 0.77 | CASP6 (0.41) | HPGDHSD17B10ALDH1A1POLBKDM4E | |
| SCHEMBL22080751 | 0.77 | ALDH1A1 (0.60) | HPGDHSD17B10ALDH1A1POLBACHE | |
| SCHEMBL10913894 | 0.77 | AHR (0.47) | HPGDHSD17B10ALDH1A1POLBKDM4E | |
| SCHEMBL10913972 | 0.76 | ALOX5 (0.56) | POLBACHEKDM4EPKM | |
| SCHEMBL3774059 | 0.74 | ALDH1A1 (0.52) | HPGDALDH1A1MAPK1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |