Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911817 | 0.92 | LMNA (0.45) | PKMLMNAALDH1A1HPGDKMT2A | |
| SCHEMBL10913473 | 0.88 | PDK2 (0.44) | PKMLMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL10911899 | 0.86 | POLB (0.44) | PKMLMNAALDH1A1KDM4EHSD17B10 | |
| Dimethylamine SCHEMBL10909955 | 0.83 | RAB9A (0.43) | LMNAALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL10914087 | 0.83 | RAB9A (0.43) | LMNAALDH1A1KDM4EHPGDKMT2A | |
| Nitric Acid SCHEMBL10909522 | 0.83 | POLB (0.43) | LMNAALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10909553 | 0.82 | POLB (0.45) | PKMLMNAALDH1A1KDM4EHSD17B10 | |
| Diethylamine SCHEMBL10909563 | 0.81 | RAB9A (0.42) | LMNAALDH1A1KDM4EHPGDKMT2A | |
| Diethylamine SCHEMBL10911789 | 0.81 | POLB (0.41) | LMNAALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10912915 | 0.81 | RPS6KA2 (0.47) | LMNAALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |