Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909553 | 0.94 | POLB (0.45) | PDK2MTNR1AMTNR1BHSD17B10USP2 | |
| SCHEMBL10911817 | 0.90 | LMNA (0.45) | POLBLMNAPKMALDH1A1HPGD | |
| SCHEMBL10912235 | 0.88 | PKM (0.43) | HSD17B10POLBLMNAPKMALDH1A1 | |
| SCHEMBL10914087 | 0.87 | RAB9A (0.43) | POLBLMNAALDH1A1HPGDRAB9A | |
| SCHEMBL10911899 | 0.84 | POLB (0.44) | HSD17B10MAPK1POLBLMNAPKM | |
| Dimethylamine SCHEMBL10909955 | 0.82 | RAB9A (0.43) | POLBLMNAALDH1A1HPGDRAB9A | |
| SCHEMBL10912064 | 0.82 | PDK2 (0.45) | PDK2HSD17B10MAPK1POLBALDH1A1 | |
| Nitric Acid SCHEMBL10909522 | 0.82 | POLB (0.43) | HSD17B10MAPK1POLBLMNAALDH1A1 | |
| Dimethylamine SCHEMBL10909606 | 0.81 | RPS6KA2 (0.51) | HSD17B10MAPK1POLBLMNAALDH1A1 | |
| Diethylamine SCHEMBL10909563 | 0.81 | RAB9A (0.42) | POLBLMNAALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |