Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913473 | 0.94 | PDK2 (0.44) | POLBALDH1A1MTNR1AMTNR1BMAPK1 | |
| SCHEMBL10911899 | 0.90 | POLB (0.44) | POLBALDH1A1KDM4EMEN1HTT | |
| SCHEMBL10911817 | 0.84 | LMNA (0.45) | POLBALDH1A1KMT2ARAB9AL3MBTL1 | |
| Dimethylamine SCHEMBL10913831 | 0.83 | POLB (0.46) | POLBALDH1A1KDM4EMEN1HTT | |
| SCHEMBL10914345 | 0.83 | POLB (0.44) | POLBALDH1A1KDM4EMEN1HTT | |
| SCHEMBL10912235 | 0.82 | PKM (0.43) | POLBALDH1A1KDM4EMEN1KMT2A | |
| Dimethylamine SCHEMBL10912051 | 0.82 | RPS6KA2 (0.49) | POLBALDH1A1KDM4EMEN1HTT | |
| Diethylamine SCHEMBL10913285 | 0.81 | POLB (0.44) | POLBALDH1A1KDM4EMEN1HTT | |
| SCHEMBL10912529 | 0.81 | POLB (0.43) | POLBALDH1A1KDM4EMEN1HTT | |
| SCHEMBL10913826 | 0.81 | TERT (0.47) | POLBALDH1A1KDM4EMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |