Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 8/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367374 | 0.83 | CA1 (0.38) | LMNATDP1 | |
| SCHEMBL9215888 | 0.83 | KDM4E (0.35) | RXRARXRBRXRGKDM4EJAK2 | |
| SCHEMBL7682354 | 0.81 | DRD1 (0.50) | DRD1DRD2DRD4DRD5DRD3 | |
| SCHEMBL13069720 | 0.73 | ALDH1A1 (0.52) | DRD1DRD2DRD4RXRARXRB | |
| SCHEMBL19337507 | 0.73 | L3MBTL1 (0.53) | DRD2DRD4DRD3RXRARXRB | |
| SCHEMBL8991056 | 0.73 | CA1 (0.62) | KDM4ELMNAMAPTMTNR1AMTNR1B | |
| SCHEMBL7938418 | 0.73 | L3MBTL1 (0.38) | GAAL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL10910618 | 0.72 | DRD1 (0.39) | DRD1LMNAMAPTKMT2A | |
| SCHEMBL10339423 | 0.72 | KDM4E (0.39) | RXRARXRBRXRGKDM4EMAPT | |
| Bromide SCHEMBL7964464 | 0.71 | DRD1 (0.38) | DRD1DRD2DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600787-A | Process for the preparation of aromatic compounds which contain perfluorinated side-chains bonded via a heteroatom | BAYER AKTIENGESELLSCHAFT (DE) | 1986-07-15 | — | — | US | claimed |