Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 18/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913013 | 0.92 | SMN1; SMN2 (0.34) | PTPN11CDC7DBF4 | |
| SCHEMBL10915061 | 0.91 | PTPN11 (0.41) | PTPN11CDC7DBF4PANK3 | |
| SCHEMBL10910998 | 0.84 | LMNA (0.37) | — | |
| SCHEMBL10921995 | 0.84 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL10914725 | 0.82 | CPB1 (0.36) | — | |
| SCHEMBL10911009 | 0.82 | TDP1 (0.39) | — | |
| SCHEMBL10910590 | 0.82 | LDHA (0.38) | PTPN11 | |
| SCHEMBL10914513 | 0.82 | DPP4 (0.34) | — | |
| SCHEMBL10912905 | 0.81 | CYP1A2 (0.39) | — | |
| SCHEMBL10914514 | 0.79 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088940-B1 | PYRIDINE-CARBOXYLIC-ACID ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BAYER AG (DE) | 1986-05-21 | — | — | EP | disclosed |
| EP-0088938-B1 | USE OF PYRIDINE COMPOUNDS FOR THE MANUFACTURE OF MEDICAMENTS WITH AN ANTIHYPOXEMIA AND ISCHEMIA-PROTECTIVE ACTIVITY | BAYER AG (DE) | 1986-04-30 | — | — | EP | disclosed |
| EP-0088938-A1 | Use of pyridine compounds for the manufacture of medicaments with an antihypoxemia and ischemia-protective activity | BAYER AG (DE) | 1983-09-21 | — | — | EP | disclosed |