Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.48 |
| ▸ | MMP9 | P14780 | 8/20 | 0.48 |
| ▸ | MMP3 | P08254 | 6/20 | 0.48 |
| ▸ | MMP13 | P45452 | 6/20 | 0.48 |
| ▸ | MMP1 | P03956 | 4/20 | 0.48 |
| ▸ | MMP7 | P09237 | 4/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10612379 | 0.92 | MMP9 (0.46) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL10614339 | 0.91 | MMP13 (0.43) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL9221798 | 0.87 | TDP1 (0.57) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL6514467 | 0.87 | TDP1 (0.57) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL5173100 | 0.87 | TDP1 (0.57) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL10611069 | 0.82 | TDP1 (0.49) | MMP2MMP9MMP3MMP13MMP1 | |
| Imidazole SCHEMBL28169637 | 0.80 | TDP1 (0.49) | MMP2MMP9MMP3MMP13SLC1A3 | |
| Imidazole SCHEMBL7269081 | 0.80 | TDP1 (0.49) | MMP2MMP9MMP3MMP13SLC1A3 | |
| SCHEMBL10614350 | 0.80 | MMP9 (0.50) | MMP2MMP9MMP3MMP13MMP1 | |
| SCHEMBL10586916 | 0.79 | TDP1 (0.44) | MMP2MMP9MMP3MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193904-A2 | Amino acid derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-09-10 | — | — | EP | disclosed |