Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 10/20 | 0.50 |
| ▸ | MMP9 | P14780 | 9/20 | 0.50 |
| ▸ | MMP13 | P45452 | 3/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9221798 | 1.00 | TDP1 (0.57) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL5173100 | 1.00 | TDP1 (0.57) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL10611069 | 0.92 | TDP1 (0.49) | TDP1MMP2MMP9MMP13MMP3 | |
| Imidazole SCHEMBL7269081 | 0.92 | TDP1 (0.49) | TDP1MMP2MMP9MMP13MMP3 | |
| Imidazole SCHEMBL28169637 | 0.92 | TDP1 (0.49) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL7382028 | 0.90 | TSHR (0.50) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL7335677 | 0.88 | KCNA5 (0.45) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL10586916 | 0.88 | TDP1 (0.44) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL10612379 | 0.87 | MMP9 (0.46) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL10914765 | 0.87 | MMP2 (0.48) | TDP1MMP2MMP9MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019208721-A1 | HAIR MOISTURIZER, WHITENING AGENT, AND WHITENING COSMETIC | 株式会社成和化成 (JP) | 2019-10-31 | — | — | WO | disclosed |
| US-20050026827-A1 | Octapeptide bombesin analogs | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, SAS, A PARIS, FRANCE | 2005-02-03 | — | — | US | disclosed |
| US-20030050436-A1 | Octapeptide bombesin analogs | BIOMEASURE INC., MASSACHUSETTS CORPORATION | 2003-03-13 | — | — | US | disclosed |
| US-6307017-B1 | Octapeptide bombesin analogs | BIOMEASURE, INCORPORATED | 2001-10-23 | — | — | US | disclosed |
| EP-0489089-B1 | THERAPEUTIC PEPTIDES | BIOMEASURE INC (US) | 1996-06-19 | — | — | EP | disclosed |
| EP-0480969-A4 | AMINO ACID ANALOG CCK ANTAGONISTS | — | 1993-01-07 | — | — | EP | disclosed |
| EP-0480969-A1 | AMINO ACID ANALOG CCK ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-04-22 | — | — | EP | disclosed |
| WO-1991002746-A1 | THERAPEUTIC PEPTIDES | BIOMEASURE, INC. (US) | 1991-03-07 | — | — | WO | disclosed |
| WO-1991000725-A2 | AMINO ACID ANALOG CCK ANTAGONISTS | ABBOTT LABORATORIES (US) | 1991-01-24 | — | — | WO | disclosed |
| US-4734400-A | BRONCHODILATION WITHOUT CARDIOVASCULAR SIDE EFFECTS | HOFFMANN-LA ROCHE INC. (US) | 1988-03-29 | — | — | US | disclosed |
| US-4605641-A | BRONCHODILATOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1986-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050436-A1 | Octapeptide bombesin analogs | GRPR, GHRHR, VGF | TDP1 4151/4885MMP2 1708/4885MMP9 3199/4885 |
| US-20050026827-A1 | Octapeptide bombesin analogs | GRPR, VGF, GHRHR | TDP1 4219/4885MMP2 1954/4885MMP9 2896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.