SCHEMBL5173100

SCHEMBL5173100

Cc1ccc(S(=O)(=O)N[C@@H](Cc2c[nH]cn2)C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.57
▸ MMP2 P08253 10/20 0.50
▸ MMP9 P14780 9/20 0.50
▸ MMP13 P45452 3/20 0.47
▸ MMP3 P08254 2/20 0.47
▸ ADAMTS4 O75173 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ POLB P06746 1/20 0.46
▸ SLC1A3 P43003 1/20 0.45
▸ SLC1A2 P43004 1/20 0.45
▸ SLC1A1 P43005 1/20 0.45
▸ ADAM17 P78536 3/20 0.45
▸ MMP14 P50281 1/20 0.45
▸ MMP1 P03956 1/20 0.44
▸ MMP7 P09237 1/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ L3MBTL1 Q9Y468 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6514467 1.00 TDP1 (0.57) TDP1MMP2MMP9MMP13MMP3
SCHEMBL9221798 1.00 TDP1 (0.57) TDP1MMP2MMP9MMP13MMP3
SCHEMBL10611069 0.92 TDP1 (0.49) TDP1MMP2MMP9MMP13MMP3
Imidazole SCHEMBL7269081 0.92 TDP1 (0.49) TDP1MMP2MMP9MMP13MMP3
Imidazole SCHEMBL28169637 0.92 TDP1 (0.49) TDP1MMP2MMP9MMP13MMP3
SCHEMBL7382028 0.90 TSHR (0.50) TDP1MMP2MMP9MMP13MMP3
SCHEMBL7335677 0.88 KCNA5 (0.45) TDP1MMP2MMP9MMP13MMP3
SCHEMBL10586916 0.88 TDP1 (0.44) TDP1MMP2MMP9MMP13MMP3
SCHEMBL10612379 0.87 MMP9 (0.46) TDP1MMP2MMP9MMP13MMP3
SCHEMBL10914765 0.87 MMP2 (0.48) TDP1MMP2MMP9MMP13MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113698457-B Preparation method of gonadorelin acetate 上海丽珠制药有限公司 2024-06-11 — — CN claimed
EP-1029073-B1 METHOD AND AGENT FOR DETERMINING DEAMINASE ACTIVITY BIO MERIEUX (FR) 2007-05-09 — — EP claimed
US-6733986-B1 IMPORTANT IN MEDICINE, AGRIFOODS INDUSTRY, ENVIRONMENTAL CONTROL BIO MERIEUX (FR) 2004-05-11 — — US claimed
EP-1029073-A1 METHOD AND AGENT FOR DETERMINING AN ENZYMATIC ACTIVITY SUCH AS DEAMINASE BIO MERIEUX (FR) 2000-08-23 — — EP claimed
WO-1999024604-A1 METHOD AND AGENT FOR DETERMINING AN ENZYMATIC ACTIVITY SUCH AS DEAMINASE BIO MERIEUX (FR) 1999-05-20 — — WO claimed
CN-113698457-B Preparation method of gonadorelin acetate 上海丽珠制药有限公司 2024-06-11 — — CN disclosed
EP-1029073-B1 METHOD AND AGENT FOR DETERMINING DEAMINASE ACTIVITY BIO MERIEUX (FR) 2007-05-09 — — EP disclosed
US-20050026827-A1 Octapeptide bombesin analogs SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, SAS, A PARIS, FRANCE 2005-02-03 — — US disclosed
US-6733986-B1 IMPORTANT IN MEDICINE, AGRIFOODS INDUSTRY, ENVIRONMENTAL CONTROL BIO MERIEUX (FR) 2004-05-11 — — US disclosed
US-20030050436-A1 Octapeptide bombesin analogs BIOMEASURE INC., MASSACHUSETTS CORPORATION 2003-03-13 — — US disclosed
US-6307017-B1 Octapeptide bombesin analogs BIOMEASURE, INCORPORATED 2001-10-23 — — US disclosed
EP-1029073-A1 METHOD AND AGENT FOR DETERMINING AN ENZYMATIC ACTIVITY SUCH AS DEAMINASE BIO MERIEUX (FR) 2000-08-23 — — EP disclosed
EP-0233838-A2 Neurite-promoting factor and process for the manufacture thereof INCYTE PHARMACEUTICALS, INC. (US) 1987-08-26 — — EP disclosed
WO-1987004349-A1 PEPTIDE ANALOGS DELLARIA JOSEPH 1987-07-30 — — WO disclosed
US-4605641-A BRONCHODILATOR AGENTS HOFFMANN-LA ROCHE INC. (US) 1986-08-12 — — US disclosed
EP-0188214-A2 Novel growth hormone-releasing peptides and method of treating mammals therewith The Administrators of The Tulane University Educational Fund (US) 1986-07-23 — — EP disclosed
EP-0173481-A2 Peptides THE UPJOHN COMPANY (US) 1986-03-05 — — EP disclosed
EP-0168042-A2 Dihydroorotic acid derivatives, processes for their preparing and pharmaceutical composition containing them TANABE SEIYAKU CO., LTD. (JP) 1986-01-15 — — EP disclosed
EP-0136475-A2 Novel growth hormone-releasing peptides and method of treating mammals therewith The Administrators of The Tulane University Educational Fund (US) 1985-04-10 — — EP disclosed
EP-0119153-A2 Synthetic vaccines THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1984-09-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030050436-A1 Octapeptide bombesin analogs GRPR, GHRHR, VGF TDP1 4151/4885MMP2 1708/4885MMP9 3199/4885
US-20050026827-A1 Octapeptide bombesin analogs GRPR, VGF, GHRHR TDP1 4219/4885MMP2 1954/4885MMP9 2896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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