Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 9/20 | 0.44 |
| ▸ | MMP9 | P14780 | 8/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL28169637 | 1.00 | TDP1 (0.49) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL6514467 | 0.92 | TDP1 (0.57) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL9221798 | 0.92 | TDP1 (0.57) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL5173100 | 0.92 | TDP1 (0.57) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL10611069 | 0.85 | TDP1 (0.49) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL7382028 | 0.82 | TSHR (0.50) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL7335677 | 0.81 | KCNA5 (0.45) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL10586916 | 0.81 | TDP1 (0.44) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL10612379 | 0.80 | MMP9 (0.46) | TDP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL10914765 | 0.80 | MMP2 (0.48) | TDP1MMP2MMP9MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |