Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11951339 | 0.83 | CA1 (0.56) | CA1CA2CA12CA9CYP4F2 | |
| SCHEMBL10918857 | 0.82 | CA1 (0.55) | CA1CA2CA12CA9CYP4F2 | |
| SCHEMBL17008983 | 0.79 | ALDH1A1 (0.56) | CYP4F2CYP4A11BAZ2BBAZ2AALDH1A1 | |
| SCHEMBL15320746 | 0.78 | ALOX15 (0.64) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL30508547 | 0.78 | CA1 (0.51) | CA1CA2CA12CA9CYP4F2 | |
| SCHEMBL4681116 | 0.78 | CA1 (0.51) | CA1CA2CA12CA9CYP4F2 | |
| SCHEMBL11716438 | 0.77 | CYP4F2 (0.55) | CA1CA2CA12CA9CYP4F2 | |
| SCHEMBL1817672 | 0.75 | CA1 (0.51) | CA1CA2CA12CA9CYP4F2 | |
| SCHEMBL7762382 | 0.75 | CA1 (0.51) | CA1CA2CA12CA9CYP4F2 | |
| SCHEMBL29039368 | 0.75 | CA1 (0.51) | CA1CA2CA12CA9CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232579-B | As insecticide and acaricidal indole carboxamides and benzimidazole-carboxamide | 拜耳作物科学股份公司 | 2018-11-23 | — | — | CN | disclosed |
| US-9802895-B2 | Indole and benzimidazolecarboxamides as insecticides and acaricides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-10-31 | — | — | US | disclosed |
| EP-3107896-A1 | INDOLE CARBOXAMIDES AND BENZIMIDAZOLE CARBOXAMIDES AS INSECTICIDES AND ACARICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-12-28 | — | — | EP | disclosed |
| CN-106232579-A | As insecticide and acaricidal indole carboxamides and benzimidazole-carboxamide | 拜耳作物科学股份公司 | 2016-12-14 | — | — | CN | disclosed |
| US-20160355476-A1 | Indole and benzimidazolecarboxamides as insecticides and acaricides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-12-08 | — | — | US | disclosed |
| WO-2015121406-A1 | INDOLE CARBOXAMIDES AND BENZIMIDAZOLE CARBOXAMIDES AS INSECTICIDES AND ACARICIDES | BAYER CROPSCIENCE AG (DE) | 2015-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160355476-A1 | Indole and benzimidazolecarboxamides as insecticides and acaricides | ACHE, AADAC, IDO1 | CA1 1078/4885CA2 691/4885CA12 2825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.