Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203437 | 1.00 | PKM (0.44) | PKML3MBTL1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3853115 | 1.00 | PKM (0.44) | PKML3MBTL1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL203436 | 1.00 | PKM (0.44) | PKML3MBTL1HPGDSMN1; SMN2ALDH1A1 | |
| Symclosene SCHEMBL8096505 | 0.89 | HPGD (0.40) | PKML3MBTL1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL11290710 | 0.82 | SMN1; SMN2 (0.42) | PKML3MBTL1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL10923681 | 0.77 | SMN1; SMN2 (0.45) | PKML3MBTL1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL27640914 | 0.74 | PKM (0.47) | PKML3MBTL1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL18181485 | 0.72 | PKM (0.46) | PKML3MBTL1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL742011 | 0.72 | PKM (0.46) | PKML3MBTL1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL204494 | 0.72 | PKM (0.58) | PKML3MBTL1HPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055474-B1 | THE USE OF BETA-SULFONYLACRYLIC ACID DERIVATIVES ON A DRY BLEND CONTAINING THEM OR PELLETS MADE THEREFROM IN SYNTHETIC POLYMERS | STAUFFER CHEMICAL COMPANY (US) | 1986-04-30 | — | — | EP | disclosed |
| US-4424167-A | Process for the preparation of 2,3-dichlorosulphonyl-acrylonitriles | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-03 | — | — | US | disclosed |
| US-4395371-A | MICROBIOCIDES MADE FROM 2,2-DIHALOGENO-3-SULPHONYL PROPIONITRILE AND WATER | BAYER AKTIENGESELLSCHAFT (DE) | 1983-07-26 | — | — | US | disclosed |