SCHEMBL203436

SCHEMBL203436

N#C/C(Cl)=C(/Cl)S(=O)(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
HPGD P15428 3/20 0.43
SMN1; SMN2 Q16637 5/20 0.42
ALDH1A1 P00352 5/20 0.42
KMT2A Q03164 5/20 0.42
MEN1 O00255 4/20 0.42
HSD17B10 Q99714 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
KDM4E B2RXH2 2/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
ALPG P10696 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
HTT P42858 1/20 0.41
TSHR P16473 1/20 0.40
MAPT P10636 3/20 0.39
LMNA P02545 1/20 0.39
DUSP3 P51452 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203437 1.00 PKM (0.44) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL3853115 1.00 PKM (0.44) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL10923673 1.00 PKM (0.44) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
Symclosene SCHEMBL8096505 0.89 HPGD (0.40) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL11290710 0.82 SMN1; SMN2 (0.42) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL10923681 0.77 SMN1; SMN2 (0.45) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL27640914 0.74 PKM (0.47) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL18181485 0.72 PKM (0.46) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL742011 0.72 PKM (0.46) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL204494 0.72 PKM (0.58) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012076699-A1 BIOCIDE MICROCAPSULE FORMULATIONS CONTAINING STABILISED IODINE-CONTAINING COMPOUNDS LANXESS DEUTSCHLAND GMBH (DE) 2012-06-14 WO claimed
EP-2462805-A1 Formulations containing stabilised compounds containing iodine LANXESS Deutschland GmbH (DE) 2012-06-13 EP claimed
US-11566140-B2 Exterior coating composition TROY CORPORATION (US) 2023-01-31 US disclosed
US-20200377738-A1 EXTERIOR COATING COMPOSITION TROY CORPORATION (US) 2020-12-03 US disclosed
WO-2020243293-A1 EXTERIOR COATING COMPOSITION TROY CORPORATION (US) 2020-12-03 WO disclosed
US-10798940-B2 Penflufen polymer particles LANXESS DEUTSCHLAND GMBH (DE) 2020-10-13 US disclosed
EP-3428148-B1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) 2020-07-08 EP disclosed
EP-3344663-B1 POLYMER PARTICLE CONTAINING PENFLUFEN LANXESS DEUTSCHLAND GMBH (DE) 2020-02-19 EP disclosed
EP-3344664-B1 BIOCIDAL MIXTURES LANXESS DEUTSCHLAND GMBH (DE) 2019-09-25 EP disclosed
US-10231459-B2 Penflufen as a wood preservative against wood-destroying basidiomycetes LANXESS DEUTSCHLAND GMBH (DE) 2019-03-19 US disclosed
EP-3428148-A1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF Merial, Inc. (US) 2019-01-16 EP disclosed
WO-1995026962-A1 THIAZOLYLPYRAZOLINONES AND THEIR USE FOR PROTECTING TECHNICAL MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1995-10-12 WO disclosed
WO-1995021526-A1 USE OF 1,3,2-BENZODITHIAZOL-1-OXIDES AS MICROBIOCIDES FOR PROTECTING TECHNICAL MATERIALS, AND CERTAIN 1,3,2-BENZODITHIAZOL-1-OXIDES BAYER AKTIENGESELLSCHAFT (DE) 1995-08-17 WO disclosed
WO-1995014558-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-06-01 WO disclosed
WO-1995014383-A1 ALKYL-N-PYRROLES BAYER AKTIENGESELLSCHAFT (DE) 1995-06-01 WO disclosed
WO-1995011786-A1 TIMBER PROTECTING MEDIUM CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-05-04 WO disclosed
WO-1995006091-A1 MOULD-RESISTANT EMULSION PAINTS BAYER AKTIENGESELLSCHAFT (DE) 1995-03-02 WO disclosed
WO-1995004722-A1 THIOCARBAMOYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1995-02-16 WO disclosed
WO-1994021734-A1 PAINTS CONTAINING n-ALKYL-N-AZOLS AS PRESERVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1994-09-29 WO disclosed
EP-0277402-B1 BIOCIDE W.R. Grace & Co.-Conn. (US) 1991-09-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10798940-B2 Penflufen polymer particles FAP, PUF60, MATR3 PKM 767/4885L3MBTL1 3954/4885HPGD 96/4885
US-10231459-B2 Penflufen as a wood preservative against wood-destroying basidiomycetes BLVRB, DCXR, PAH PKM 636/4885L3MBTL1 2584/4885HPGD 1001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.