SCHEMBL27640914

SCHEMBL27640914

N#CC(=O)S(=O)(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
HPGD P15428 3/20 0.46
SMN1; SMN2 Q16637 4/20 0.45
KMT2A Q03164 4/20 0.45
ALDH1A1 P00352 4/20 0.45
MEN1 O00255 3/20 0.45
HSD17B10 Q99714 3/20 0.45
KDM4E B2RXH2 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
POLB P06746 1/20 0.45
GAA P10253 1/20 0.45
ALPG P10696 1/20 0.45
ALOX15 P16050 1/20 0.45
ALOX12 P18054 1/20 0.45
TSHR P16473 1/20 0.44
HTR6 P50406 1/20 0.42
MAPT P10636 2/20 0.42
HTT P42858 1/20 0.41
CA1 P00915 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL742011 0.77 PKM (0.46) PKML3MBTL1HPGDSMN1; SMN2KMT2A
SCHEMBL18181485 0.77 PKM (0.46) PKML3MBTL1HPGDSMN1; SMN2KMT2A
SCHEMBL7266697 0.74 SMN1; SMN2 (0.55) SMN1; SMN2KMT2AALDH1A1HSD17B10TDP1
SCHEMBL3828442 0.74 SMN1; SMN2 (0.55) SMN1; SMN2ALDH1A1HSD17B10TDP1TSHR
SCHEMBL11068541 0.74 SMN1; SMN2 (0.40) PKMSMN1; SMN2ALDH1A1HSD17B10TDP1
SCHEMBL3853115 0.74 PKM (0.44) PKML3MBTL1HPGDSMN1; SMN2KMT2A
SCHEMBL14345876 0.74 PKM (0.59) PKML3MBTL1HPGDSMN1; SMN2KMT2A
SCHEMBL203437 0.74 PKM (0.44) PKML3MBTL1HPGDSMN1; SMN2KMT2A
SCHEMBL8076171 0.74 L3MBTL1 (0.44) PKML3MBTL1HPGDSMN1; SMN2KMT2A
SCHEMBL10923681 0.74 SMN1; SMN2 (0.45) PKML3MBTL1HPGDSMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1741989-A Organic activator PROCTER & GAMBLE (US) 2006-03-01 CN disclosed