Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28764074 | 0.89 | HPGD (0.41) | PKML3MBTL1HPGDALDH1A1KMT2A | |
| SCHEMBL11879645 | 0.80 | TSHR (0.47) | PKMALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11152641 | 0.80 | HPGD (0.47) | PKMHPGDALDH1A1KMT2AHSD17B10 | |
| SCHEMBL28938490 | 0.78 | KMT2A (0.44) | L3MBTL1HPGDALDH1A1KMT2AHSD17B10 | |
| SCHEMBL12220338 | 0.77 | TDP1 (0.53) | PKML3MBTL1HPGDALDH1A1KMT2A | |
| SCHEMBL10599045 | 0.77 | SMN1; SMN2 (0.55) | L3MBTL1ALDH1A1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL27640914 | 0.77 | PKM (0.47) | PKML3MBTL1HPGDALDH1A1KMT2A | |
| SCHEMBL9276097 | 0.76 | KIF11 (0.43) | KMT2AMEN1MAPTCA1CA2 | |
| SCHEMBL29432580 | 0.76 | ALDH1A1 (0.49) | HPGDALDH1A1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL18181485 | 0.75 | PKM (0.46) | PKML3MBTL1HPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138356-B2 | Chemical inhibitors of inhibitors of differentiation | Angiogeney, Inc. (US) | 2012-03-20 | — | — | US | disclosed |
| US-8039532-B2 | Heterocyclic compound, ultraviolet absorbent and composition containing the same | FUJIFILM CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |
| US-20100210762-A1 | HETEROCYCLIC COMPOUND, ULTRAVIOLET ABSORBENT AND COMPOSITION CONTAINING THE SAME | FUJIFILM CORPORATION (JP) | 2010-08-19 | — | — | US | disclosed |
| US-20100130638-A1 | ULTRAVIOLET ABSORBENT COMPOSITION | FUJIFILM CORPORATION (JP) | 2010-05-27 | — | — | US | disclosed |
| US-20100025642-A1 | ULTRAVIOLET ABSORBENT COMPOSITION | FUJIFILM CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20090240067-A1 | METHOD OF PRODUCING A BISBENZODITHIOL COMPOUND | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20090226422-A1 | Chemical Inhibitors of Inhibitors of Differentiation | ANGIOGENEX | 2009-09-10 | — | — | US | disclosed |
| US-20090181948-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |
| US-7138108-B2 | Photoprotective UV-screening compositions comprising (phenylsulfonyl) acrylonitrile-substituted silanes/siloxanes | L'OREAL (FR) | 2006-11-21 | — | — | US | disclosed |
| WO-1995024190-A2 | RECEPTOR TYROSINE KINASE INHIBITORS FOR INHIBITING CELL PROLIFERATIVE DISORDERS AND COMPOSITIONS THEREOF | SUGEN, INC. (US) | 1995-09-14 | — | — | WO | disclosed |
| US-5308608-A | Compounds for destroying viruses, cells and tissues | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1994-05-03 | — | — | US | disclosed |
| US-5149708-A | Useful for detection and treatment of malignant cells, combined with irradiation | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1992-09-22 | — | — | US | disclosed |
| EP-0476011-A1 | PHOTOSENSITIZING DIELS-ALDER PORPHYRIN DERIVATIVES | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1992-03-25 | — | — | EP | disclosed |
| WO-1990015059-A1 | PHOTOSENSITIZING DIELS-ALDER PORPHYRIN DERIVATIVES | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1990-12-13 | — | — | WO | disclosed |
| US-4093644-A | MICROBIOCIDES | THE DOW CHEMICAL COMPANY (US) | 1978-06-06 | — | — | US | disclosed |
| US-4049694-A | BACTERICIDE, FUNGICIDE | THE DOW CHEMICAL COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
| US-4049696-A | BACTERICIDE, FUNGICIDE | THE DOW CHEMICAL COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
| US-4049695-A | BACTERICIDE, FUNGICIDE | THE DOW CHEMICAL COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
| US-3976668-A | MICROBIOCIDE | SANITIZED, INC. (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210762-A1 | HETEROCYCLIC COMPOUND, ULTRAVIOLET ABSORBENT AND COMPOSITION CONTAINING THE SAME | F12, F2, CYP24A1 | PKM 4094/4885L3MBTL1 3500/4885HPGD 547/4885 |
| US-20090181948-A1 | DIAMINE DERIVATIVE | ARG1, PRMT5, PRMT1 | PKM 3834/4885L3MBTL1 2665/4885HPGD 349/4885 |
| US-20090240067-A1 | METHOD OF PRODUCING A BISBENZODITHIOL COMPOUND | SQOR, NQO1, PBRM1 | PKM 1051/4885L3MBTL1 2663/4885HPGD 785/4885 |
| US-20090226422-A1 | Chemical Inhibitors of Inhibitors of Differentiation | BRAF, MAPK1, RAF1 | PKM 2593/4885L3MBTL1 2309/4885HPGD 3243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.