SCHEMBL203437

SCHEMBL203437

N#CC(Cl)=C(Cl)S(=O)(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
HPGD P15428 3/20 0.43
SMN1; SMN2 Q16637 5/20 0.42
ALDH1A1 P00352 5/20 0.42
KMT2A Q03164 5/20 0.42
MEN1 O00255 4/20 0.42
HSD17B10 Q99714 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
KDM4E B2RXH2 2/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
ALPG P10696 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
HTT P42858 1/20 0.41
TSHR P16473 1/20 0.40
MAPT P10636 3/20 0.39
LMNA P02545 1/20 0.39
DUSP3 P51452 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3853115 1.00 PKM (0.44) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL203436 1.00 PKM (0.44) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL10923673 1.00 PKM (0.44) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
Symclosene SCHEMBL8096505 0.89 HPGD (0.40) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL11290710 0.82 SMN1; SMN2 (0.42) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL10923681 0.77 SMN1; SMN2 (0.45) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL27640914 0.74 PKM (0.47) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL18181485 0.72 PKM (0.46) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL742011 0.72 PKM (0.46) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1
SCHEMBL204494 0.72 PKM (0.58) PKML3MBTL1HPGDSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012076699-A1 BIOCIDE MICROCAPSULE FORMULATIONS CONTAINING STABILISED IODINE-CONTAINING COMPOUNDS LANXESS DEUTSCHLAND GMBH (DE) 2012-06-14 WO claimed
EP-2462805-A1 Formulations containing stabilised compounds containing iodine LANXESS Deutschland GmbH (DE) 2012-06-13 EP claimed
EP-0051198-A1 Method for the preparation of 2-halo-3-sulfonyl-acrylonitriles and their use BAYER AG (DE) 1982-05-12 EP claimed
US-12604900-B2 Penflufen as a wood preservative against wood- destroying basidiomy cetes LANXESS DEUTSCHLAND GMBH (DE) 2026-04-21 US disclosed
CN-113873886-B Overcoating composition 特洛伊公司 2024-10-18 CN disclosed
US-20230337680-A1 PENFLUFEN AS A WOOD PRESERVATIVE AGAINST WOOD-DESTROYING BASIDIOMYCETES LANXESS DEUTSCHLAND GMBH (DE) 2023-10-26 US disclosed
US-11723368-B2 Penflufen as a wood preservative against wood-destroying basidiomycetes LANHESS Deutshcland GmbH 2023-08-15 US disclosed
US-11566140-B2 Exterior coating composition TROY CORPORATION (US) 2023-01-31 US disclosed
CN-113873886-A Overcoat compositions 特洛伊公司 2021-12-31 CN disclosed
CN-108077275-B Fungicidal penflufen mixtures 朗盛德国有限责任公司 2021-04-30 CN disclosed
WO-2020243293-A1 EXTERIOR COATING COMPOSITION TROY CORPORATION (US) 2020-12-03 WO disclosed
WO-1994021734-A1 PAINTS CONTAINING n-ALKYL-N-AZOLS AS PRESERVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1994-09-29 WO disclosed
EP-0277402-B1 BIOCIDE W.R. Grace & Co.-Conn. (US) 1991-09-11 EP disclosed
EP-0277402-A1 Biocide W.R. Grace & Co.-Conn. (US) 1988-08-10 EP disclosed
EP-0055474-B1 THE USE OF BETA-SULFONYLACRYLIC ACID DERIVATIVES ON A DRY BLEND CONTAINING THEM OR PELLETS MADE THEREFROM IN SYNTHETIC POLYMERS STAUFFER CHEMICAL COMPANY (US) 1986-04-30 EP disclosed
EP-0051198-B1 METHOD FOR THE PREPARATION OF 2-HALO-3-SULFONYL-ACRYLONITRILES AND THEIR USE BAYER AG (DE) 1984-01-25 EP disclosed
US-4424167-A Process for the preparation of 2,3-dichlorosulphonyl-acrylonitriles BAYER AKTIENGESELLSCHAFT (DE) 1984-01-03 US disclosed
EP-0051202-B1 PROCESS FOR PREPARING 2,3-DICHLORO-SULFONYL ACRYLONITRILES BAYER AG (DE) 1983-11-09 EP disclosed
US-4395371-A MICROBIOCIDES MADE FROM 2,2-DIHALOGENO-3-SULPHONYL PROPIONITRILE AND WATER BAYER AKTIENGESELLSCHAFT (DE) 1983-07-26 US disclosed
EP-0051202-A1 Process for preparing 2,3-dichloro-sulfonyl acrylonitriles BAYER AG (DE) 1982-05-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11723368-B2 Penflufen as a wood preservative against wood-destroying basidiomycetes BLVRB, DCXR, PAH PKM 636/4885L3MBTL1 2584/4885HPGD 1001/4885
US-20230337680-A1 PENFLUFEN AS A WOOD PRESERVATIVE AGAINST WOOD-DESTROYING BASIDIOMYCETES BLVRB, DCXR, PAH PKM 636/4885L3MBTL1 2584/4885HPGD 1001/4885
US-12604900-B2 Penflufen as a wood preservative against wood- destroying basidiomy cetes PSENEN, CMA1, PSEN1 PKM 571/4885L3MBTL1 2770/4885HPGD 1755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.