SCHEMBL10923939

SCHEMBL10923939

CCCCCCCCSc1ncc2[nH]cnc2n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 3/20 0.49
PAK1 Q13153 1/20 0.49
KDM4E B2RXH2 2/20 0.48
MEN1 O00255 1/20 0.48
GAA P10253 1/20 0.48
TSHR P16473 1/20 0.48
HTT P42858 1/20 0.48
KMT2A Q03164 1/20 0.48
HSD17B10 Q99714 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
POLA1 P09884 1/20 0.44
SMN1; SMN2 Q16637 4/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
QPCT Q16769 1/20 0.40
HASPIN Q8TF76 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27535767 0.94 XDH (0.47) XDHPAK1KDM4EMEN1GAA
SCHEMBL7592034 0.82 ALDH1A1 (0.49) XDHPAK1KDM4EMEN1KMT2A
SCHEMBL30729987 0.80 ALDH1A1 (0.47) XDHPAK1KDM4EMEN1KMT2A
SCHEMBL10923930 0.77 KDM4E (0.48) XDHPAK1KDM4EMEN1GAA
SCHEMBL5144928 0.74 XDH (0.56) XDHPAK1KDM4EMEN1GAA
SCHEMBL1371022 0.73 ALDH1A1 (0.53) PAK1KDM4EMEN1KMT2AHSD17B10
SCHEMBL3691693 0.73 POLA1 (0.51) XDHPAK1KDM4EHTTPOLA1
SCHEMBL11802315 0.72 ALDH1A1 (0.57) PAK1KDM4EGAAHSD17B10POLA1
SCHEMBL30661721 0.72 POLA1 (0.47) XDHPAK1KDM4EHTTPOLA1
SCHEMBL2563787 0.72 ALDH1A1 (0.45) PAK1KDM4EMEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0069507-B1 HYDROCARBON COMPOSITIONS CONTAINING HETEROAROMATIC NITROGEN COMPOUNDS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-09-10 EP disclosed
EP-0069507-A2 Hydrocarbon compositions containing heteroaromatic nitrogen compounds EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-01-12 EP disclosed
US-4367152-A Selected heteroaromatic nitrogen compounds as antioxidant/metal deactivators/electrical insulators in lubricating oils and petroleum liquid fuels EXXON RESEARCH AND ENGINEERING CO. (US) 1983-01-04 US disclosed