Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925626 | 0.81 | MAPT (0.44) | POLBMAPTAKR1C3ALDH1A1LMNA | |
| SCHEMBL10925475 | 0.81 | AKR1C3 (0.46) | AKR1C1RAB9APOLBNPC1MAPT | |
| SCHEMBL10924367 | 0.81 | ALDH1A1 (0.49) | AKR1C1RAB9APOLBPKMMAPT | |
| SCHEMBL10925523 | 0.74 | MAPT (0.41) | NPC1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10923755 | 0.74 | MAPT (0.41) | NPC1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10923477 | 0.74 | MAPT (0.41) | NPC1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL679854 | 0.72 | MCL1 (0.50) | MCL1RAB9APOLBNPC1PKM | |
| SCHEMBL762892 | 0.72 | MCL1 (0.50) | MCL1RAB9APOLBNPC1PKM | |
| SCHEMBL5168254 | 0.72 | MCL1 (0.50) | MCL1RAB9APOLBNPC1PKM | |
| SCHEMBL60843 | 0.72 | MAPT (0.76) | MCL1RAB9APOLBNPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4598083-A | INSECTICIDES, NEMATOCIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-07-01 | — | — | US | disclosed |