Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | KIF20A | O95235 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925626 | 0.81 | MAPT (0.44) | AKR1C3ALDH1A1NPSR1KDM4EMAPT | |
| SCHEMBL10924367 | 0.81 | ALDH1A1 (0.49) | AKR1C3AKR1C2AKR1C1ALDH1A1NPSR1 | |
| SCHEMBL10925092 | 0.81 | MCL1 (0.46) | AKR1C3AKR1C2AKR1C1ALDH1A1NPSR1 | |
| SCHEMBL11761824 | 0.75 | GABRA1 (0.58) | ALDH1A1NPSR1KDM4EMAPTMEN1 | |
| SCHEMBL11761830 | 0.75 | GABRA1 (0.58) | ALDH1A1NPSR1KDM4EMAPTMEN1 | |
| SCHEMBL987696 | 0.74 | MAPT (0.77) | ALDH1A1NPSR1KDM4EMAPTMEN1 | |
| SCHEMBL9446456 | 0.72 | MAPT (0.48) | ALDH1A1NPSR1KDM4EMAPTMEN1 | |
| SCHEMBL9446459 | 0.72 | MAPT (0.48) | ALDH1A1NPSR1KDM4EMAPTMEN1 | |
| SCHEMBL11553035 | 0.72 | EGFR (0.46) | ALDH1A1NPSR1KDM4EMAPTMEN1 | |
| SCHEMBL11553040 | 0.72 | EGFR (0.46) | ALDH1A1NPSR1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4598083-A | INSECTICIDES, NEMATOCIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-07-01 | — | — | US | disclosed |