Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KIF20A | O95235 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925626 | 0.81 | MAPT (0.44) | ALDH1A1MAPTGAAL3MBTL1MEN1 | |
| SCHEMBL10925475 | 0.81 | AKR1C3 (0.46) | ALDH1A1MAPTHTTL3MBTL1MEN1 | |
| SCHEMBL10925092 | 0.81 | MCL1 (0.46) | ALDH1A1MAPTHTTL3MBTL1PKM | |
| SCHEMBL26552234 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MAPTATMHTTGAA | |
| SCHEMBL3368837 | 0.74 | ALDH1A1 (0.77) | ALDH1A1MAPTATMHTTGAA | |
| SCHEMBL22330666 | 0.72 | TRPA1 (0.44) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL10923477 | 0.71 | MAPT (0.41) | ALDH1A1MAPTLMNATHRB | |
| SCHEMBL10923755 | 0.71 | MAPT (0.41) | ALDH1A1MAPTLMNATHRB | |
| SCHEMBL10925523 | 0.71 | MAPT (0.41) | ALDH1A1MAPTLMNATHRB | |
| SCHEMBL11350306 | 0.71 | ALDH1A1 (0.62) | ALDH1A1MAPTATMHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4598083-A | INSECTICIDES, NEMATOCIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-07-01 | — | — | US | disclosed |