Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10926600 | 0.89 | ALDH1A1 (0.47) | CYP19A1ALDH1A1LMNATP53CYP1A2 | |
| SCHEMBL10925526 | 0.88 | CYP17A1 (0.41) | TBXAS1CYP19A1ALDH1A1LMNATP53 | |
| Hydrochloric Acid SCHEMBL10928283 | 0.87 | CYP17A1 (0.50) | TBXAS1CYP19A1ALDH1A1LMNACYP1A2 | |
| SCHEMBL10925022 | 0.86 | HMOX1 (0.43) | TBXAS1CYP19A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10926324 | 0.86 | ALDH1A1 (0.51) | CYP19A1ALDH1A1LMNAMAPT | |
| SCHEMBL10925380 | 0.86 | L3MBTL1 (0.43) | TBXAS1CYP19A1ALDH1A1LMNACYP1A2 | |
| SCHEMBL10929722 | 0.86 | GRM5 (0.43) | TBXAS1CYP19A1ALDH1A1LMNACYP1A2 | |
| SCHEMBL10928100 | 0.86 | MAPT (0.51) | CNR1TBXAS1CYP19A1LMNAKCNH2 | |
| Methylamine SCHEMBL10925751 | 0.86 | HTR7 (0.47) | TBXAS1CYP19A1ALDH1A1LMNATP53 | |
| SCHEMBL10927606 | 0.86 | TBXAS1 (0.48) | TBXAS1ALDH1A1LMNATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518607-A | FUNGICIDES, BACXTERICIDES AND ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1985-05-21 | — | — | US | disclosed |