Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132324 | 0.85 | LMNA (0.46) | LMNAALDH1A1POLBHPGDGAA | |
| SCHEMBL29407499 | 0.85 | LMNA (0.52) | LMNAALDH1A1POLBHPGDGAA | |
| SCHEMBL3134108 | 0.83 | LMNA (0.44) | LMNAALDH1A1POLBHPGDGAA | |
| SCHEMBL21217233 | 0.83 | LMNA (0.44) | LMNAALDH1A1POLBHPGDCA12 | |
| SCHEMBL1202392 | 0.83 | LMNA (0.44) | LMNAALDH1A1POLBHPGDCA12 | |
| SCHEMBL5355206 | 0.83 | LMNA (0.44) | LMNAALDH1A1POLBHPGDCA12 | |
| SCHEMBL4648086 | 0.83 | LMNA (0.44) | LMNAALDH1A1POLBHPGDCA12 | |
| SCHEMBL8420703 | 0.82 | LMNA (0.38) | LMNAALDH1A1 | |
| SCHEMBL21802606 | 0.81 | GPR84 (0.44) | LMNAALDH1A1POLBHPGDGAA | |
| SCHEMBL1232870 | 0.80 | ALDH1A1 (0.41) | LMNAALDH1A1POLBHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368763-B1 | 4-MERCAPTO BUTYRAMIDES N-MONO OR N,N-DISUBSTITUTED BY A MONO OR POLYHYDROXYALKYL RADICAL, AND THEIR USE AS REDUCING AGENTS IN THE PROCESS OF PERMANENT DEFORMATION OF THE HAIR | L'OREAL (FR) | 1992-10-14 | — | — | EP | claimed |