SCHEMBL1387475

SCHEMBL1387475

O=C(CO)N(CCO)CCO

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
MAPT P10636 2/20 0.33
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALOX15 P16050 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH2 P05091 1/20 0.32
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28912905 0.84 ALDH1A1 (0.46) POLBCA12CA1CA2CA9
SCHEMBL1232870 0.81 ALDH1A1 (0.41) POLBCA12CA1CA2CA9
SCHEMBL10990860 0.81 POLB (0.39) POLBCA12CA1CA2CA9
SCHEMBL12888849 0.80 POLB (0.31) POLB
SCHEMBL1387473 0.79 POLB (0.38) POLBCA12CA1CA2CA9
SCHEMBL1387466 0.79 ALDH1A1 (0.39) POLBCA12CA1CA2CA9
SCHEMBL3108822 0.77 POLB (0.37) POLBCA12CA1CA2CA9
SCHEMBL6539776 0.77 ALDH1A1 (0.54) POLBCA12CA1CA2CA9
SCHEMBL3628031 0.77 POLB (0.41) POLBCA12CA1CA2CA9
SCHEMBL10926752 0.77 POLB (0.37) POLBCA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170362454-A1 WATER BASED MAGNETIC INK CHARACTER RECOGNITION INK JET INK BASED ON DISPERSION OF FUNCTIONALIZED NANOPARTICULATE MAGNETIC FERRITE NANUM NANOTECNOLOGIA S/A (BR) 2017-12-21 US claimed
US-20160208120-A1 WATER BASED MAGNETIC INK CHARACTER RECOGNITION INK JET INK BASED ON DISPERSION OF FUNCTIONALIZED NANOPARTICULATE MAGNETIC FERRITE NANUM NANOTECNOLOGIA S/A (BR) 2016-07-21 US claimed
US-9133070-B2 Smokeless propellant composition containing bismuth-based compound and method of preparing the same AGENCY FOR DEFENSE DEVELOPMENT (KR) 2015-09-15 US claimed
US-20140338803-A1 SMOKELESS PROPELLANT COMPOSITION CONTAINING BISMUTH-BASED COMPOUND AND METHOD OF PREPARING THE SAME AGENCY FOR DEFENSE DEVELOPMANT (KR) 2014-11-20 US claimed
EP-0733045-B1 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS ASTRAZENECA AB (SE) 2001-08-16 EP claimed
US-5880130-A TREATMENT OF CELL-PROLIFERATION DISEASES ZENECA LIMITED (GB) 1999-03-09 US claimed
JP-H09506363-A 1997-06-24 JP claimed
EP-0733045-A1 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS ZENECA LIMITED (GB) 1996-09-25 EP claimed
WO-1995015952-A1 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS ZENECA LIMITED (GB) 1995-06-15 WO claimed
US-5179124-A Nonsteroid antiinflammatory agents UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1993-01-12 US claimed
US-4143159-A SKIN-CARE AGENTS CONTAINING HYDROXYALKYL CARBOXAMIDES AND PROCESS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1979-03-06 US claimed
US-20200308109-A1 FLUORENE COMPOUND AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC (JP) 2020-10-01 US disclosed
US-20190177271-A1 FLUORENE COMPOUND AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC (JP) 2019-06-13 US disclosed
WO-2018122495-A1 ENERGETIC COMPOSITION COMPRISING AN AMORPHOUS BORON NANOSTRUCTURED MATERIAL SORBONNE UNIVERSITE (FR) 2018-07-05 WO disclosed
US-9981992-B2 Compositions and methods for reduction of ketones, aldehydes and iminiums, and products produced thereby THE BOARD OF TRUSTEES OF NORTHERN ILLINOIS UNIVERSITY (US) 2018-05-29 US disclosed
US-5417895-A Bonding agents for HTPB-type solid propellants AEROJET GENERAL CORPORATION (US) 1995-05-23 US disclosed
US-5179124-A Nonsteroid antiinflammatory agents UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1993-01-12 US disclosed
US-4464392-A Process for controlling antimicrobial activity using glycolic acid derivatives THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1984-08-07 US disclosed
US-4347378-A Antimicrobial glycolic acid derivatives THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1982-08-31 US disclosed
US-4346043-A BIOSTATS IN COMMERCIAL PRODUCTS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF AGRICULTURE (US) 1982-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190177271-A1 FLUORENE COMPOUND AND PHARMACEUTICAL USE THEREOF FH, PCK2, PC POLB 1201/4885CA12 2660/4885CA1 1930/4885
US-20200308109-A1 FLUORENE COMPOUND AND PHARMACEUTICAL USE THEREOF FH, PCK2, PC POLB 1201/4885CA12 2660/4885CA1 1930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.