Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29839908 | 0.85 | ABCG2 (0.54) | ABCG2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL2620726 | 0.85 | ABCG2 (0.54) | ABCG2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL26661232 | 0.79 | KDM4E (0.65) | ABCG2KDM4ECYP3A4LMNATP53 | |
| 3-Methyl-2-Phenyl-4H-Chromen-4-One SCHEMBL694139 | 0.79 | ALDH1A1 (0.68) | ABCG2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL28567447 | 0.78 | ABCG2 (0.45) | ABCG2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL10929651 | 0.75 | ADORA3 (0.47) | ABCG2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL29839875 | 0.74 | LMNA (0.61) | ABCG2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL29839889 | 0.74 | LMNA (0.61) | ABCG2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL28887973 | 0.74 | CYP3A4 (0.40) | ABCG2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL28381233 | 0.72 | KMT2A (0.49) | ABCG2KDM4ECYP3A4LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60023379-A | — | — | None | — | — | JP | disclosed |
| JP-S6023379-A | NOVEL METHYLTHIOFLAVONE COMPOUND SUBSTITUTED AT 3-POSITION AND ITS PREPARATION | SHIN NIPPON YAKUHIN KK | 1985-02-05 | — | — | JP | disclosed |