Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26661232 | 0.76 | KDM4E (0.65) | KMT2AKDM4EMEN1CYP3A4LMNA | |
| SCHEMBL10929274 | 0.72 | ABCG2 (0.49) | KMT2AKDM4EMEN1CYP3A4LMNA | |
| SCHEMBL27932665 | 0.72 | CA1 (0.47) | KMT2AKDM4EMEN1CYP3A4LMNA | |
| Flavonol SCHEMBL16150505 | 0.71 | KDM4E (0.88) | KMT2AKDM4EMEN1CYP3A4LMNA | |
| SCHEMBL10929651 | 0.69 | ADORA3 (0.47) | KMT2AKDM4EMEN1CYP3A4LMNA | |
| SCHEMBL28567447 | 0.69 | ABCG2 (0.45) | KMT2AKDM4EMEN1CYP3A4LMNA | |
| SCHEMBL2396767 | 0.69 | ABCG2 (0.64) | KMT2AKDM4EMEN1CYP3A4LMNA | |
| SCHEMBL31314572 | 0.68 | RAB9A (0.70) | KMT2AKDM4EMEN1CYP3A4LMNA | |
| SCHEMBL28381234 | 0.68 | KMT2A (0.57) | KMT2AKDM4EMEN1CYP3A4LMNA | |
| SCHEMBL11733201 | 0.68 | KDM4E (0.73) | KMT2AKDM4EMEN1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903319-B | Preparation method of 2-phosphonothioflavonoid compound | 信阳农林学院 | 2022-06-14 | — | — | CN | disclosed |
| CN-110903319-A | Preparation method of 2-phosphonothioflavonoid compound | 信阳农林学院 | 2020-03-24 | — | — | CN | disclosed |