Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10925679 | 0.94 | SMN1; SMN2 (0.43) | MAPK1LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL10993952 | 0.86 | SMN1; SMN2 (0.48) | MAPK1LMNAKMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL10926536 | 0.85 | NPC1 (0.47) | MAPK1LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL10930333 | 0.83 | ALDH1A1 (0.40) | MAPK1L3MBTL1LMNAKMT2AALDH1A1 | |
| SCHEMBL10925857 | 0.83 | ALDH1A1 (0.54) | LMNAALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL10926181 | 0.81 | LMNA (0.60) | LMNAKMT2APKMKCNH2 | |
| SCHEMBL10925160 | 0.78 | LMNA (0.57) | MAPK1LMNAKMT2APKMMAPT | |
| SCHEMBL10927399 | 0.78 | TSHR (0.39) | LMNATSHRHRH3 | |
| SCHEMBL10992668 | 0.77 | MAPT (0.50) | LMNAKMT2AALDH1A1MAPTCASP1 | |
| SCHEMBL10929942 | 0.77 | ALDH1A1 (0.47) | LMNAKMT2AALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562186-A | HYPOTENSIVE, ANALGESICS, AND ANTIINFLAMMATORY AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-12-31 | — | — | US | claimed |
| EP-0189080-A2 | (1,2,4-Oxadiazol-3-YL)-arylmethanones, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-07-30 | — | — | EP | disclosed |
| US-4562186-A | HYPOTENSIVE, ANALGESICS, AND ANTIINFLAMMATORY AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-12-31 | — | — | US | disclosed |