Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925916 | 0.91 | LMNA (0.57) | ALDH1A1LMNAHTTNPSR1CYP3A4 | |
| SCHEMBL10926181 | 0.88 | LMNA (0.60) | LMNAHTTNPSR1CYP3A4CYP2C9 | |
| SCHEMBL10925160 | 0.88 | LMNA (0.57) | LMNAHTTNPSR1CYP3A4CYP2C9 | |
| SCHEMBL10930333 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTNPSR1CYP3A4 | |
| SCHEMBL10927224 | 0.82 | ACHE (0.46) | LMNAHTTNPSR1MC4RCACNA1B | |
| SCHEMBL10928162 | 0.80 | LMNA (0.66) | LMNAHTTNPSR1CYP3A4CYP2C9 | |
| SCHEMBL10930339 | 0.77 | MAPK1 (0.40) | ALDH1A1LMNAKCNH2KMT2AMAPT | |
| SCHEMBL10993952 | 0.77 | SMN1; SMN2 (0.48) | ALDH1A1LMNAHTTNPSR1MEN1 | |
| Hydrochloric Acid SCHEMBL10926536 | 0.76 | NPC1 (0.47) | ALDH1A1LMNAHTTNPSR1MEN1 | |
| SCHEMBL10925857 | 0.74 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562186-A | HYPOTENSIVE, ANALGESICS, AND ANTIINFLAMMATORY AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-12-31 | — | — | US | claimed |
| EP-0189080-A2 | (1,2,4-Oxadiazol-3-YL)-arylmethanones, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-07-30 | — | — | EP | disclosed |
| US-4562186-A | HYPOTENSIVE, ANALGESICS, AND ANTIINFLAMMATORY AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-12-31 | — | — | US | disclosed |