Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 3/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10926536 | 0.99 | NPC1 (0.47) | SMN1; SMN2ALDH1A1NPC1RAB9AHSD17B10 | |
| Hydrochloric Acid SCHEMBL10925679 | 0.92 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1NPC1RAB9AHSD17B10 | |
| SCHEMBL10930339 | 0.86 | MAPK1 (0.40) | ALDH1A1LMNAMAPTKMT2AMAPK1 | |
| SCHEMBL10925857 | 0.85 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL10930333 | 0.83 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1NPC1RAB9AHTT | |
| SCHEMBL10926181 | 0.80 | LMNA (0.60) | HTTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL10992668 | 0.79 | MAPT (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL10925160 | 0.78 | LMNA (0.57) | SMN1; SMN2HTTLMNAMAPTMEN1 | |
| SCHEMBL10924892 | 0.77 | LMNA (0.51) | SMN1; SMN2ALDH1A1NPC1RAB9ACD274 | |
| SCHEMBL10929942 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HTTLMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562186-A | HYPOTENSIVE, ANALGESICS, AND ANTIINFLAMMATORY AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-12-31 | — | — | US | claimed |