Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10926181 | 0.84 | LMNA (0.60) | LMNAHTTNPSR1KMT2APOLB | |
| SCHEMBL10930339 | 0.83 | MAPK1 (0.40) | ALDH1A1MAPTLMNAKMT2AL3MBTL1 | |
| SCHEMBL10993952 | 0.83 | SMN1; SMN2 (0.48) | ALDH1A1MAPTLMNAHTTNPSR1 | |
| SCHEMBL10929942 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHTTNPSR1 | |
| SCHEMBL10925160 | 0.82 | LMNA (0.57) | MAPTLMNAHTTNPSR1KMT2A | |
| Hydrochloric Acid SCHEMBL10926536 | 0.82 | NPC1 (0.47) | ALDH1A1MAPTLMNAHTTNPSR1 | |
| SCHEMBL10925857 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL10927393 | 0.79 | LMNA (0.43) | ALDH1A1LMNAPOLBSMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL10925679 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1MAPTLMNAHTTNPSR1 | |
| SCHEMBL10992668 | 0.76 | MAPT (0.50) | ALDH1A1MAPTLMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562186-A | HYPOTENSIVE, ANALGESICS, AND ANTIINFLAMMATORY AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-12-31 | — | — | US | claimed |
| EP-0189080-A2 | (1,2,4-Oxadiazol-3-YL)-arylmethanones, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-07-30 | — | — | EP | disclosed |
| US-4562186-A | HYPOTENSIVE, ANALGESICS, AND ANTIINFLAMMATORY AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-12-31 | — | — | US | disclosed |