Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10929989 | 0.85 | AKR1B1 (0.56) | AKR1B1PDK2AKR1A1KMT2A | |
| SCHEMBL10345954 | 0.80 | AKR1B1 (0.55) | AKR1B1PDK2AKR1A1CRBNKMT2A | |
| SCHEMBL8804611 | 0.72 | AKR1B1 (1.00) | AKR1B1AKR1A1 | |
| SCHEMBL9672186 | 0.71 | AKR1B1 (0.56) | AKR1B1AKR1A1CRBN | |
| SCHEMBL2483457 | 0.68 | AKR1B1 (0.56) | AKR1B1KMT2A | |
| SCHEMBL2484250 | 0.66 | AKR1B1 (0.52) | AKR1B1 | |
| SCHEMBL9751299 | 0.65 | AKR1B1 (0.39) | AKR1B1PDK2KMT2A | |
| SCHEMBL10345515 | 0.65 | AKR1B1 (0.55) | AKR1B1PDK2AKR1A1 | |
| SCHEMBL9674028 | 0.64 | AKR1B1 (0.40) | AKR1B1AKR1A1 | |
| SCHEMBL9383374 | 0.64 | AKR1B1 (0.81) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537892-A | ANTIDIABETIC AGENTS | ALCON LABORATORIES, INC. (US) | 1985-08-27 | — | — | US | claimed |