Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13054604 | 0.78 | SMN1; SMN2 (0.50) | CTSBHDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL13054596 | 0.78 | SMN1; SMN2 (0.50) | CTSBHDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL7300117 | 0.76 | HDAC2 (0.51) | CTSBHDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL16360050 | 0.73 | SMN1; SMN2 (0.55) | CTSBHDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL19791859 | 0.70 | HDAC2 (0.54) | CTSBHDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL7772333 | 0.67 | ALDH1A1 (0.66) | HDAC2HDAC8HDAC6SMN1; SMN2CNR2 | |
| SCHEMBL13054598 | 0.67 | CTSB (0.53) | CTSBHDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL21549032 | 0.67 | CTSB (0.53) | CTSBHDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL8357482 | 0.67 | CTSB (0.67) | CTSBHDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL24114487 | 0.66 | SMN1; SMN2 (0.58) | HDAC2HDAC8HDAC6SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027258-B1 | PHOSPHORYL MURAMYL PEPTIDES, METHOD FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | CIBA-GEIGY AG (CH) | 1985-05-15 | — | — | EP | disclosed |
| US-4409209-A | POTENTIATION OF ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1983-10-11 | — | — | US | disclosed |
| US-4323560-A | IMMUNOPOTENTIATING ACTION TO INCREASE ANTIBIOTIC EFFECTIVENESS | CIBA-GEIGY CORPORATION (US) | 1982-04-06 | — | — | US | disclosed |
| EP-0027258-A1 | Phosphoryl muramyl peptides, method for their preparation and their use in medicines | CIBA-GEIGY AG (CH) | 1981-04-22 | — | — | EP | disclosed |