Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | IL1B | P01584 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21549032 | 1.00 | CTSB (0.53) | CTSBHDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL8357482 | 0.88 | CTSB (0.67) | CTSBHDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL7431065 | 0.86 | CASP1 (0.63) | CTSBHDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL13055700 | 0.84 | CNR2 (0.56) | HDAC8HDAC6CYP1A2 | |
| SCHEMBL16566049 | 0.80 | F2 (0.56) | CTSBHDAC2HDAC8HDAC6 | |
| SCHEMBL5689690 | 0.80 | HDAC2 (0.59) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL19791859 | 0.79 | HDAC2 (0.54) | CTSBHDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL18759250 | 0.79 | CTSB (0.55) | CTSBHDAC2HDAC8HDAC6MAPT | |
| SCHEMBL10725495 | 0.79 | CTSB (0.57) | CTSBHDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL14341581 | 0.78 | CTSG (0.60) | CTSBHDAC2HDAC8HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311711-A1 | Inhibitors of NAAA and Methods Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311711-A1 | Inhibitors of NAAA and Methods Thereof | NAAA, NAA50, FAAH | CTSB 537/4885HDAC2 465/4885HDAC8 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.