Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | BHMT | Q93088 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | EYA2 | O00167 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | MVD | P53602 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331219 | 0.83 | BHMT (0.37) | BHMTTDP1EYA2APPACE | |
| SCHEMBL22693656 | 0.83 | BHMT (0.37) | BHMTTDP1EYA2APPACE | |
| SCHEMBL10044471 | 0.80 | ALDH1A1 (0.42) | CA12CA1CA2CA9PIK3CD | |
| SCHEMBL12448092 | 0.78 | CA1 (0.38) | CA12CA1CA2CA9PIK3CD | |
| SCHEMBL12977350 | 0.78 | CA1 (0.38) | CA12CA1CA2CA9PIK3CD | |
| SCHEMBL8417238 | 0.78 | CA1 (0.38) | CA12CA1CA2CA9PIK3CD | |
| SCHEMBL22061 | 0.78 | TDP1 (0.47) | BHMTTDP1EYA2APPACE | |
| SCHEMBL16941101 | 0.78 | BHMT (0.45) | BHMTTDP1EYA2APPACE | |
| SCHEMBL20158619 | 0.78 | TDP1 (0.52) | CA12CA1CA2CA9PIK3CD | |
| SCHEMBL16576609 | 0.78 | TDP1 (0.41) | CA12CA1CA2CA9PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118684592-A | Tetracycline derivatives, preparation method thereof and application thereof in antibacterial aspect | 中国医学科学院药物研究所 | 2024-09-24 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11034684-B2 | Isoxazole analogs as FXR agonists and methods of use thereof | ENANTA PHARMACEUTICALS, INC. (US) | 2021-06-15 | — | — | US | disclosed |
| US-10774071-B2 | PD-1/PD-L1 inhibitors | GILEAD SCIENCES, INC. (US) | 2020-09-15 | — | — | US | disclosed |
| US-20200017471-A1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES, INC. | 2020-01-16 | — | — | US | disclosed |
| US-9809621-B2 | Stable peptide-based PACE4 inhibitors | SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) | 2017-11-07 | — | — | US | disclosed |
| US-20150218110-A1 | USE OF SUBSTITUTED BENZODIAZEPINONES AND BENZAZEPINONES OR THE SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-08-06 | — | — | US | disclosed |
| US-20150218110-A1 | USE OF SUBSTITUTED BENZODIAZEPINONES AND BENZAZEPINONES OR THE SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-08-06 | — | — | US | disclosed |
| US-20150141324-A1 | STABLE PEPTIDE-BASED FURIN INHIBITORS | SOCPRA Sciences Sante et Humaines S.E.C. (CA) | 2015-05-21 | — | — | US | disclosed |
| US-20140206622-A1 | STABLE PEPTIDE-BASED PACE4 INHIBITORS | SOCPRA Sciences Sante et Humaines S.E.C. (CA) | 2014-07-24 | — | — | US | disclosed |
| WO-2014066936-A9 | SUPRAMOLECULAR STRUCTURE | MONASH UNIVERSITY (AU) | 2014-07-10 | — | — | WO | disclosed |
| WO-2014066936-A1 | SUPRAMOLECULAR STRUCTURE | MONASH UNIVERSITY (AU) | 2014-05-08 | — | — | WO | disclosed |
| US-8268827-B2 | Pyridazinone derivatives as PARP inhibitors | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA. (IT) | 2012-09-18 | — | — | US | disclosed |
| US-20100261709-A1 | PYRIDAZINONE DERIVATIVES AS PARP INHIBITORS | MSD ITALIA S.R.L. (IT) | 2010-10-14 | — | — | US | disclosed |
| EP-0081301-B1 | A STERICALLY HINDERED AMINO ACID PROMOTED ACID GAS SCRUBBING PROCESS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4405579-A | CARBON DIOXIDE, ABSORPTION | EXXON RESEARCH AND ENGINEERING CO. (US) | 1983-09-20 | — | — | US | disclosed |
| EP-0081301-A1 | A sterically hindered amino acid promoted acid gas scrubbing process | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1983-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10774071-B2 | PD-1/PD-L1 inhibitors | PDCD1, CD274, PDCD1LG2 | CA12 1897/4885CA1 2634/4885CA2 3798/4885 |
| US-20150141324-A1 | STABLE PEPTIDE-BASED FURIN INHIBITORS | FURIN, PREP, VIP | CA12 1511/4885CA1 1473/4885CA2 3785/4885 |
| US-20140206622-A1 | STABLE PEPTIDE-BASED PACE4 INHIBITORS | FURIN, DNPEP, PRAP1 | CA12 3894/4885CA1 4206/4885CA2 4541/4885 |
| US-20150218110-A1 | USE OF SUBSTITUTED BENZODIAZEPINONES AND BENZAZEPINONES OR THE SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | GABBR1, GABRA1, GABRA6 | CA12 4515/4885CA1 3378/4885CA2 1196/4885 |
| US-20100261709-A1 | PYRIDAZINONE DERIVATIVES AS PARP INHIBITORS | PARP1, PARP2, PARP3 | CA12 4884/4885CA1 4879/4885CA2 4846/4885 |
| US-20200017471-A1 | PD-1/PD-L1 INHIBITORS | PDCD1, CD274, PDCD1LG2 | CA12 1897/4885CA1 2634/4885CA2 3798/4885 |
| US-11034684-B2 | Isoxazole analogs as FXR agonists and methods of use thereof | GPBAR1, SLC10A1, NR1H4 | CA12 3445/4885CA1 2164/4885CA2 2228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.