Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 1/20 | 0.55 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572076 | 0.87 | ROCK2 (0.55) | ALDH1A1HIF1AMAPTKDM4EMEN1 | |
| SCHEMBL7572085 | 0.84 | RECQL (0.58) | INSRIGF1RALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL7571372 | 0.84 | INSR (0.58) | INSRIGF1RALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL7571488 | 0.80 | HPGD (0.62) | INSRIGF1RALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL13122225 | 0.78 | INSR (0.55) | INSRIGF1RALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL14911289 | 0.77 | SYK (0.52) | HPGDRAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2083483 | 0.76 | ALDH1A1 (0.60) | INSRIGF1RALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL13122034 | 0.76 | INSR (0.67) | INSRIGF1RALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL11934937 | 0.76 | ROCK2 (0.51) | ALDH1A1HIF1AMAPTKDM4EMEN1 | |
| SCHEMBL7572900 | 0.75 | INSR (0.56) | INSRIGF1RALDH1A1HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4507488-A | N-Pyrazolylalkylenediamine intermediates | BOEHRINGER MANNHEIM GMBH (DE) | 1985-03-26 | — | — | US | disclosed |
| EP-0042592-B1 | N-HETEROARYLALKYLENE DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE | Roche Diagnostics GmbH (DE) | 1985-01-30 | — | — | EP | disclosed |