Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31531726 | 0.82 | GABRG2 (0.46) | GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2580052 | 0.82 | GABRG2 (0.46) | GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL16731967 | 0.80 | ALDH1A1 (0.32) | — | |
| SCHEMBL28301379 | 0.76 | IDO1 (0.44) | — | |
| SCHEMBL6017122 | 0.72 | ALDH1A1 (0.52) | — | |
| SCHEMBL45025 | 0.72 | IDO1 (0.43) | — | |
| SCHEMBL30332425 | 0.72 | NISCH (0.38) | GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8894535 | 0.72 | NOTUM (0.43) | GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL22344712 | 0.72 | LMNA (0.47) | — | |
| SCHEMBL6769901 | 0.72 | KDM4E (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4497951-A | Ethynyl-phenylene-substituted-1,3,5-triazine derivatives and process for their production | HUGHES AIRCRAFT COMPANY (US) | 1985-02-05 | — | — | US | disclosed |
| US-4442278-A | Ethynyl-substituted s-triazine derivatives, polymers thereof and process for making the same | HUGHES AIRCRAFT COMPANY (US) | 1984-04-10 | — | — | US | disclosed |