Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | USP8 | P40818 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31531726 | 1.00 | GABRG2 (0.46) | GABRG2GABRB3GABRA3GABRA5ESR2 | |
| SCHEMBL31275041 | 0.85 | SMN1; SMN2 (0.37) | GABRG2GABRB3GABRA3GABRA5ESR2 | |
| SCHEMBL10936686 | 0.82 | GABRG2 (0.30) | GABRG2GABRB3GABRA3GABRA5 | |
| SCHEMBL16731967 | 0.80 | ALDH1A1 (0.32) | — | |
| SCHEMBL28962149 | 0.80 | GABRG2 (0.51) | GABRG2GABRB3GABRA3GABRA5ESR2 | |
| SCHEMBL2576514 | 0.80 | KCNN4 (0.36) | GABRG2GABRB3GABRA3GABRA5 | |
| SCHEMBL7913045 | 0.72 | NPC1 (0.44) | TSHRATM | |
| SCHEMBL973015 | 0.72 | GRIA1 (0.51) | GABRG2GABRB3GABRA3GABRA5ESR2 | |
| SCHEMBL6017122 | 0.72 | ALDH1A1 (0.52) | ATRADORA2A | |
| SCHEMBL22344712 | 0.72 | LMNA (0.47) | ATRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112707871-B | Electronic active material, exciplex, organic electroluminescent device and application | 常州强力昱镭光电材料有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-112707871-A | Electronic active material, exciplex, organic electroluminescent device and application | 常州强力昱镭光电材料有限公司 | 2021-04-27 | — | — | CN | disclosed |
| EP-2560488-A1 | CERTAIN AMINO-PYRIDINES AND AMINO-TRIAZINES, COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | Cytokinetics, Inc. (US) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011133920-A1 | CERTAIN AMINO-PYRIDINES AND AMINO-TRIAZINES, COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | CYTOKINETICS, INC. (US) | 2011-10-27 | — | — | WO | disclosed |