Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31590449 | 1.00 | CASP1 (0.33) | CASP1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL6257417 | 0.95 | MAPT (0.37) | CASP1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL5267659 | 0.86 | CASP1 (0.37) | CASP1MAPTALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6570832 | 0.85 | ALDH1A1 (0.38) | CASP1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL11511986 | 0.83 | ALDH1A1 (0.49) | CASP1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL11511415 | 0.81 | CYP1A2 (0.42) | CASP1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL27696708 | 0.79 | TNFRSF1A (0.31) | CASP1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL11511993 | 0.79 | TSHR (0.46) | CASP1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL6257394 | 0.79 | ALDH1A1 (0.36) | MAPTALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL11511338 | 0.79 | ALDH1A1 (0.42) | CASP1MAPTALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12178897-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-12-31 | — | — | US | claimed |
| US-12109291-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-10-08 | — | — | US | claimed |
| US-12102704-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-10-01 | — | — | US | claimed |
| US-12097274-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-09-24 | — | — | US | claimed |
| US-11918671-B2 | Multi-tone hair dyeing method in three steps | HENKEL AG & CO. KGAA (DE) | 2024-03-05 | — | — | US | claimed |
| US-20230310296-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | HENKEL AG & CO. KGAA (DE) | 2023-10-05 | — | — | US | claimed |
| WO-2023163906-A1 | OXIDATIVE DYEING AGENT FOR KERATIN FIBERS COMPRISING NOVEL DYE PRECURSOR COMBINATIONS | HENKEL AG & CO. KGAA (DE) | 2023-08-31 | — | — | WO | claimed |
| US-20230270649-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | HENKEL AG & CO. KGAA (DE) | 2023-08-31 | — | — | US | claimed |
| WO-2023163907-A1 | OXIDATIVE DYEING AGENT FOR KERATIN FIBERS COMPRISING NOVEL DYE PRECURSOR COMBINATIONS | HENKEL AG & CO. KGAA (DE) | 2023-08-31 | — | — | WO | claimed |
| US-20230270647-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | HENKEL AG & CO. KGAA (DE) | 2023-08-31 | — | — | US | claimed |
| WO-2013013897-A2 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2013-01-31 | — | — | WO | claimed |
| WO-2013013861-A2 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2013-01-31 | — | — | WO | claimed |
| EP-1868688-A2 | OXIDATION DYES COMPRISING 2-FURANONES AND COLLAGEN (DERIVATIVES) | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-12-26 | — | — | EP | claimed |
| EP-1726289-A2 | Dyeing composition for keratin fibres which contains a reducing agent | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-11-29 | — | — | EP | claimed |
| WO-2006108505-A2 | OXIDATION DYES COMPRISING 2-FURANONES AND COLLAGEN (DERIVATIVES) | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-10-19 | — | — | WO | claimed |
| EP-1707242-A1 | Oxidative hair colouring composition comprising 1,5- and /or 2,7-dihydroxy naphthalene and at least one further coupling agent | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-10-04 | — | — | EP | claimed |
| WO-2006048069-A1 | OXIDATION DYE WITHOUT A DEVELOPER COMPONENT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-05-11 | — | — | WO | claimed |
| WO-2006018089-A1 | OXIDATION COLORANTS COMPRISING DIAMINOBENZENE DERIVATIVES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-02-23 | — | — | WO | claimed |
| EP-1585488-A1 | NOVEL PHENYLENEDIAMINE DERIVATIVE COUPLING CONSTITUENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-10-19 | — | — | EP | claimed |
| WO-2004058206-A1 | NOVEL PHENYLENEDIAMINE DERIVATIVE COUPLING CONSTITUENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12109291-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, ALDH2 | CASP1 2312/4885MAPT 1335/4885ALDH1A1 40/4885 |
| US-20230270647-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | KRT18, ALDH5A1, COX5A | CASP1 1087/4885MAPT 1359/4885ALDH1A1 28/4885 |
| US-11918671-B2 | Multi-tone hair dyeing method in three steps | TYR, HAO2, HAAO | CASP1 2586/4885MAPT 2879/4885ALDH1A1 111/4885 |
| US-20230270649-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | KRT18, ALDH5A1, COX5A | CASP1 1926/4885MAPT 984/4885ALDH1A1 37/4885 |
| US-12102704-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, ALDH2 | CASP1 2100/4885MAPT 992/4885ALDH1A1 26/4885 |
| US-12097274-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, COX5A | CASP1 1087/4885MAPT 1359/4885ALDH1A1 28/4885 |
| US-20230310296-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | KRT18, ALDH5A1, ALDH2 | CASP1 2312/4885MAPT 1335/4885ALDH1A1 40/4885 |
| US-12178897-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, COX5A | CASP1 1926/4885MAPT 984/4885ALDH1A1 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.