Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.37 |
| ▸ | INPP5B | P32019 | 1/20 | 0.37 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453764 | 0.85 | SRC (0.49) | SRCCYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL5074713 | 0.76 | SRC (0.66) | SRCCYP3A4TSHRINPPL1INPP5B | |
| SCHEMBL12770826 | 0.73 | GPR55 (0.49) | GPR55BCL2BCL2L1 | |
| Toluene SCHEMBL30760635 | 0.72 | INPPL1 (0.50) | SRCKMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL544660 | 0.72 | BCL2 (0.52) | BCL2BCL2L1LDHALDHB | |
| Benzamide SCHEMBL21771936 | 0.71 | PARP10 (0.46) | KMT2AMEN1ATMIDH1CYP3A4 | |
| SCHEMBL1099381 | 0.70 | SRC (0.51) | SRCCYP3A4TSHRSMN1; SMN2INPPL1 | |
| SCHEMBL4463680 | 0.69 | SRC (0.49) | SRCTSHRINPPL1INPP5BINPP5A | |
| SCHEMBL670158 | 0.69 | BCL2 (0.57) | CYP2C19BCL2BCL2L1SMN1; SMN2 | |
| Phosphoric Acid Monomethyl Ester SCHEMBL5375481 | 0.69 | RAPGEF4 (0.42) | KMT2AMEN1ATMCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085201-B1 | FLAME RETARDANT POLYPHENYLENE ETHER-STYRENE THERMOPLASTIC RESIN COMPOSITIONS | FMC Corporation (US) | 1985-09-11 | — | — | EP | disclosed |
| US-4446265-A | TRIARYL PHOSPHATE, 3-HYDROXYPROPYLPHOSPHINE OXIDE | FMC CORPORATION (US) | 1984-05-01 | — | — | US | disclosed |
| EP-0085201-A1 | Flame retardant polyphenylene ether-styrene thermoplastic resin compositions | FMC Corporation (US) | 1983-08-10 | — | — | EP | disclosed |
| EP-0074345-A1 | Flame retardant polyphenylene ether-styrene thermoplastic resin compositions | FMC Corporation (US) | 1983-03-16 | — | — | EP | disclosed |
| EP-0067424-A2 | Flame retardant polyphenylene ether resin compositions | FMC Corporation (US) | 1982-12-22 | — | — | EP | disclosed |
| US-4357433-A | HYDROXYALKYLPHOSPHINE OXIDE | FMC CORPORATION (US) | 1982-11-02 | — | — | US | disclosed |
| EP-0040665-A1 | Flame retardant polyphenylene oxide composition | FMC Corporation (US) | 1981-12-02 | — | — | EP | disclosed |
| US-4287119-A | CONTAINING POLYPHENYLENE OXIDE | FMC CORPORATION (US) | 1981-09-01 | — | — | US | disclosed |