Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid Monomethyl Ester SCHEMBL5678831 | 0.75 | GAA (0.64) | RAPGEF4LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL9702127 | 0.69 | BCHE (0.48) | RAPGEF4BCHEACHELMNASMN1; SMN2 | |
| SCHEMBL10940975 | 0.69 | SRC (0.45) | SMN1; SMN2BCL2MEN1KMT2ACYP2C19 | |
| Toluene SCHEMBL27468770 | 0.68 | LMNA (0.52) | ACHELMNASMN1; SMN2MEN1KMT2A | |
| Phosphoric Acid Monomethyl Ester SCHEMBL28830962 | 0.67 | SNCA (0.47) | LMNASMN1; SMN2HTTCYP1A2MEN1 | |
| SCHEMBL13407569 | 0.67 | HTT (0.66) | BCHEACHESMN1; SMN2HTTCYP1A2 | |
| SCHEMBL9820099 | 0.67 | MEN1 (0.45) | BCHEACHELMNABCL2CYP1A2 | |
| SCHEMBL13443418 | 0.66 | HTT (0.76) | BCHEACHELMNASMN1; SMN2HTT | |
| SCHEMBL13407573 | 0.66 | HTT (0.76) | BCHEACHELMNASMN1; SMN2HTT | |
| Diphenylmethane SCHEMBL9099741 | 0.66 | SMN1; SMN2 (0.54) | BCHEACHELMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244718-B2 | Water soluble prodrugs of hindered alcohols | UNIVERSITY OF KANSAS (US) | 2007-07-17 | — | — | US | disclosed |
| US-20050090431-A1 | Water soluble prodrugs of hindered alcohols | UNIVERSITY OF KANSAS (US) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090431-A1 | Water soluble prodrugs of hindered alcohols | ADH1A, ADH5, ADH1C | RAPGEF4 1701/4885BCHE 1268/4885ACHE 2968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.