Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 5/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10858291 | 0.69 | LMNA (0.38) | LMNAFDPSPGK1PGK2ADRB3 | |
| SCHEMBL7511455 | 0.69 | LMNA (0.45) | LMNAFDPSPGK1PGK2 | |
| SCHEMBL8768637 | 0.69 | LMNA (0.38) | LMNAFDPSPGK1PGK2ADRB3 | |
| SCHEMBL16143956 | 0.67 | LMNA (0.43) | LMNAFDPSPGK1PGK2 | |
| SCHEMBL5496511 | 0.65 | FDPS (0.50) | LMNAFDPSADRB3PDE4DPDE3A | |
| SCHEMBL8618015 | 0.65 | LMNA (0.35) | LMNAFDPSPGK1PGK2 | |
| SCHEMBL3936724 | 0.65 | FDPS (0.50) | LMNAFDPSADRB3PDE4DPDE3A | |
| SCHEMBL15019858 | 0.63 | FDPS (0.38) | LMNAFDPSPGK1PGK2ADRB3 | |
| SCHEMBL11489313 | 0.60 | LMNA (0.50) | LMNAFDPSPGK1PGK2ADRB3 | |
| SCHEMBL8334665 | 0.60 | LMNA (0.50) | LMNAFDPSPGK1PGK2ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068584-B1 | BORON CONTAINING POLYPHOSPHONATES FOR THE TREATMENT OF CALCIFIC TUMORS | THE PROCTER & GAMBLE COMPANY (US) | 1985-09-25 | — | — | EP | disclosed |
| EP-0068584-A1 | Boron containing polyphosphonates for the treatment of calcific tumors | THE PROCTER & GAMBLE COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |