Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 2/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10858291 | 0.77 | LMNA (0.38) | LMNAFDPSPGK1PGK2 | |
| SCHEMBL8768637 | 0.65 | LMNA (0.38) | LMNAFDPSPGK1PGK2 | |
| SCHEMBL10942002 | 0.65 | LMNA (0.38) | LMNAFDPSPGK1PGK2 | |
| SCHEMBL7511455 | 0.65 | LMNA (0.45) | LMNAFDPSPGK1PGK2 | |
| SCHEMBL3936724 | 0.61 | FDPS (0.50) | LMNAFDPS | |
| SCHEMBL5496511 | 0.61 | FDPS (0.50) | LMNAFDPS | |
| Phosphoric Acid SCHEMBL27545870 | 0.60 | — | — | |
| SCHEMBL8072145 | 0.59 | LMNA (0.44) | LMNAFDPSPGK1PGK2 | |
| SCHEMBL8334665 | 0.57 | LMNA (0.50) | LMNAFDPSPGK1PGK2 | |
| SCHEMBL11489313 | 0.57 | LMNA (0.50) | LMNAFDPSPGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831845-A4 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0831845-A1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | Elizanor Biopharmaceuticals, Inc. (US) | 1998-04-01 | — | — | EP | disclosed |